Fxr2 - FMR1 autosomal homolog 2 Gene

Also Known as Fxr2h

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23879

Summary

Predicted to enable mRNA 3'-UTR binding activity; protein dimerization activity; and translation regulator activity. Predicted to be involved in several processes, including positive regulation of response to DNA damage stimulus; regulation of filopodium assembly; and regulation of gene expression. Located in dendrite; glutamatergic synapse; and postsynapse. Part of polysome. Is expressed in central nervous system; female reproductive system; peripheral nervous system; sensory organ; and skin. Orthologous to human FXR2 (FMR1 autosomal homolog 2). [provided by Alliance of Genome Resources, Apr 2022]

Fxr2 Products (1)

mRNA Protein Name
NM_011814.2 NP_035944.2 RNA-binding protein FXR2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10567518 MGI
Biological Process GO Annotation Evidence References Source
involved in dentate gyrus development IMP
IMP: Inferred from mutant phenotype
21658585 MGI
involved in mRNA destabilization IMP
IMP: Inferred from mutant phenotype
21658585 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytoplasm IDA
IDA: Inferred from direct assay
11875043 MGI
located in dendrite IDA
IDA: Inferred from direct assay
22022532 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27770568 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
27770568 MGI
located in ribosome IDA
IDA: Inferred from direct assay
22022532 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-binding protein FXR2

fragile X mental retardation syndrome-related protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05164 FXR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fxr2 NCBI NCBI:9513