Ggt5 - gamma-glutamyltransferase 5 Gene

Also Known as GGL; Ggtla1; GGT-REL

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23887

Summary

Enables leukotriene-C(4) hydrolase. Acts upstream of or within inflammatory response and leukotriene D4 biosynthetic process. Located in plasma membrane. Orthologous to human GGT5 (gamma-glutamyltransferase 5). [provided by Alliance of Genome Resources, Apr 2022]

Ggt5 Products (2)

mRNA Protein Name
NM_001359425.1 NP_001346354.1 glutathione hydrolase 5 proenzyme isoform 2
NM_011820.5 NP_035950.2 glutathione hydrolase 5 proenzyme isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables leukotriene-C(4) hydrolase IMP
IMP: Inferred from mutant phenotype
12163373 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within inflammatory response IMP
IMP: Inferred from mutant phenotype
12163373 MGI
acts upstream of or within leukotriene D4 biosynthetic process IDA
IDA: Inferred from direct assay
9774450 MGI
acts upstream of or within leukotriene D4 biosynthetic process IMP
IMP: Inferred from mutant phenotype
12163373 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
12163373 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutathione hydrolase 5 proenzyme

  • gamma-glutamyl leukotrienase

  • gamma-glutamyltransferase-like activity 1

  • gamma-glutamyltranspeptidase 5

  • leukotriene-C4 hydrolase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05404 GGT5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19902 Ggt5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26403 Ggt5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ggt5 NCBI NCBI:2687