Kctd12 - potassium channel tetramerisation domain containing 12 Gene

Also Known as Pfet1; Pfetin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 239217

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within regulation of G protein-coupled receptor signaling pathway. Located in postsynaptic membrane and presynaptic membrane. Part of receptor complex. Is expressed in several structures, including cochlear ganglion; eye; genitourinary system; gut; and inner ear. Orthologous to human KCTD12 (Potassium Channel tetramerization domain containing 12). [provided by Alliance of Genome Resources, Apr 2022]

Kctd12 Products (2)

mRNA Protein Name
NM_177715.4 NP_808383.3 BTB/POZ domain-containing protein KCTD12
NM_177715.4 NP_808383.3 BTB/POZ domain-containing protein KCTD12

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential IDA
IDA: Inferred from direct assay
20400944 MGI
enables G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential IMP
IMP: Inferred from mutant phenotype
20400944 MGI
enables G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential IDA
IDA: Inferred from direct assay
20400944 MGI
enables G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential IMP
IMP: Inferred from mutant phenotype
20400944 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20400944 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of G protein-coupled receptor signaling pathway IGI
IGI: Inferred from genetic interaction
20400944 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
20400944 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
20400944 MGI
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
33913808 MGI
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
20400944 MGI
is active in presynaptic active zone membrane IDA
IDA: Inferred from direct assay
33913808 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
33913808 MGI
located in presynaptic membrane IDA
IDA: Inferred from direct assay
20400944 MGI
part of receptor complex IDA
IDA: Inferred from direct assay
20400944 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BTB/POZ domain-containing protein KCTD12

  • potassium channel tetramerization domain containing 12

  • predominantly fetal expressed T1 domain

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0255 Adefovir dipivoxil 99.03% Unkown

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07189 KCTD12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kctd12 NCBI NCBI:115207