Kctd12 - potassium channel tetramerisation domain containing 12 Gene

Mus musculus

Also known as Pfet1; Pfetin

Gene ID: 239217 | Gene type: protein coding

About Kctd12

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within regulation of G protein-coupled receptor signaling pathway. Located in postsynaptic membrane and presynaptic membrane. Part of receptor complex. Is expressed in several structures, including cochlear ganglion; eye; genitourinary system; gut; and inner ear. Orthologous to human KCTD12 (Potassium Channel tetramerization domain containing 12). [provided by Alliance of Genome Resources, Apr 2022]

Kctd12 Products(2)

mRNA	Protein	Name
NM_177715.4	NP_808383.3	BTB/POZ domain-containing protein KCTD12
NM_177715.4	NP_808383.3	BTB/POZ domain-containing protein KCTD12

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	IDA IDA: Inferred from direct assay	20400944	MGI
enables G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	IMP IMP: Inferred from mutant phenotype	20400944	MGI
enables G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	IDA IDA: Inferred from direct assay	20400944	MGI
enables G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	IMP IMP: Inferred from mutant phenotype	20400944	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	20400944	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within regulation of G protein-coupled receptor signaling pathway	IGI IGI: Inferred from genetic interaction	20400944	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in GABA-ergic synapse	IDA IDA: Inferred from direct assay	20400944	MGI
is active in GABA-ergic synapse	IMP IMP: Inferred from mutant phenotype	20400944	MGI
is active in postsynaptic membrane	IDA IDA: Inferred from direct assay	33913808	MGI
located in postsynaptic membrane	IDA IDA: Inferred from direct assay	20400944	MGI
is active in presynaptic active zone membrane	IDA IDA: Inferred from direct assay	33913808	MGI
is active in presynaptic membrane	IDA IDA: Inferred from direct assay	33913808	MGI
located in presynaptic membrane	IDA IDA: Inferred from direct assay	20400944	MGI
part of receptor complex	IDA IDA: Inferred from direct assay	20400944	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

BTB/POZ domain-containing protein KCTD12

potassium channel tetramerization domain containing 12

predominantly fetal expressed T1 domain

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B0255	Adefovir dipivoxil		99.03%	Unkown

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07189	KCTD12 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Kctd12	NCBI	NCBI:115207

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