2. Gene
  3. Sgcg - sarcoglycan, gamma (dystrophin-associated glycoprotein) Gene

Sgcg - sarcoglycan, gamma (dystrophin-associated glycoprotein) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 35kDa; gamma-SG; 5430420E18Rik

Gene ID: 24053 | Gene type: protein coding

About Sgcg

Summary

Predicted to be involved in cardiac muscle tissue development and heart contraction. Predicted to act upstream of or within membrane organization. Located in sarcolemma. Part of sarcoglycan complex. Is expressed in cap mesenchyme; nephrogenic interstitium; tongue; and vertebral axis musculature. Used to study autosomal recessive limb-girdle muscular dystrophy type 2C and limb-girdle muscular dystrophy. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2C and type 2 diabetes mellitus. Orthologous to human SGCG (sarcoglycan gamma). [provided by Alliance of Genome Resources, Apr 2022]

Sgcg Products(1)

mRNA Protein Name
NM_011892.3 NP_036022.1 gamma-sarcoglycan
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12189167 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
19494113 MGI
Cellular Component GO Annotation Evidence Reference Source
part of dystroglycan complex IDA
IDA: Inferred from direct assay
10678176 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10481911 MGI
part of sarcoglycan complex IDA
IDA: Inferred from direct assay
12189167 MGI
located in sarcolemma IDA
IDA: Inferred from direct assay
10678176 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-sarcoglycan

35 kDa dystrophin-associated glycoprotein

35DAG

sarcoglycan, gamma (35kD dystrophin-associated glycoprotein)

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12794 SGCG Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sgcg NCBI NCBI:6445