Carf - calcium response factor Gene

Also Known as Als2cr8; ECBRC-FC1; ECBRC-FC2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 241066

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of DNA-binding transcription factor activity. Located in granular component. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and skeletal muscle tissue. Orthologous to human CARF (calcium responsive transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Carf Products (3)

mRNA Protein Name
NM_001285463.1 NP_001272392.1 calcium-responsive transcription factor isoform 2
NM_001285473.1 NP_001272402.1 calcium-responsive transcription factor isoform 3
NM_139150.5 NP_631889.1 calcium-responsive transcription factor isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
11832226 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
11832226 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
11832226 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12154087 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11832226 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
11832226 MGI
acts upstream of or within regulation of DNA-binding transcription factor activity IGI
IGI: Inferred from genetic interaction
12154087 MGI
Cellular Component GO Annotation Evidence References Source
located in granular component IDA
IDA: Inferred from direct assay
12154087 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11832226 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calcium-responsive transcription factor

  • amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog

  • calcium-response factor CaRF

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01924 CARF Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Carf NCBI NCBI:79800