Grin3a - glutamate receptor ionotropic, NMDA3A Gene

Also Known as NR3A; GluN3A; NMDAR-L; NMDAR3A; mKIAA1973; 6430537F04; A830097C19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 242443

Summary

Enables NMDA glutamate receptor activity; Calcium Channel activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within calcium ion transport; dendrite development; and prepulse inhibition. Located in neuronal cell body and postsynaptic membrane. Is active in glutamatergic synapse. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; foot bone; and hand mesenchyme. Orthologous to human GRIN3A (glutamate ionotropic receptor NMDA type subunit 3A). [provided by Alliance of Genome Resources, Apr 2022]

Grin3a Products (2)

mRNA Protein Name
NM_001033351.2 NP_001028523.1 glutamate receptor ionotropic, NMDA 3A isoform 2 precursor
NM_001276355.1 NP_001263284.1 glutamate receptor ionotropic, NMDA 3A isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables NMDA glutamate receptor activity IMP
IMP: Inferred from mutant phenotype
14507892 MGI
enables NMDA glutamate receptor activity IPI
IPI: Inferred from physical interaction
9620802 MGI
enables calcium channel activity IDA
IDA: Inferred from direct assay
9620802 MGI
enables calcium channel activity IMP
IMP: Inferred from mutant phenotype
14507892 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9620802 MGI
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IDA
IDA: Inferred from direct assay
24183704 MGI
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IMP
IMP: Inferred from mutant phenotype
24183704 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within calcium ion transport IMP
IMP: Inferred from mutant phenotype
14507892 MGI
acts upstream of or within dendrite development IMP
IMP: Inferred from mutant phenotype
9620802 MGI
acts upstream of or within prepulse inhibition IMP
IMP: Inferred from mutant phenotype
15866554 MGI
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
25144876 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
25144876 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
24183704 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
24183704 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
14507892 MGI
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
35700736 MGI
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
9620802 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutamate receptor ionotropic, NMDA 3A

  • N-methyl-D-aspartate receptor

  • N-methyl-D-aspartate receptor subtype 3A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05806 GRIN3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grin3a NCBI NCBI:116443