Dlgap3 - DLG associated protein 3 Gene

Also Known as DAP3; DAP-3; Prpl8; Sapap3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 242667

Summary

Enables amyloid-beta binding activity. Involved in modification of synaptic structure. Located in glutamatergic synapse and neuromuscular junction. Is active in cholinergic synapse and postsynaptic specialization. Orthologous to human DLGAP3 (DLG associated protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Dlgap3 Products (2)

mRNA Protein Name
NM_001302081.1 NP_001289010.1 disks large-associated protein 3
NM_198618.5 NP_941020.1 disks large-associated protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables amyloid-beta binding IDA
IDA: Inferred from direct assay
9173930 MGI
Biological Process GO Annotation Evidence References Source
involved in modification of postsynaptic structure IDA
IDA: Inferred from direct assay
17713528 MGI
involved in modification of postsynaptic structure IEP
IEP: Inferred from expression pattern
17713528 MGI
involved in modification of postsynaptic structure IMP
IMP: Inferred from mutant phenotype
17713528 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
17713528 MGI
involved in modulation of chemical synaptic transmission IEP
IEP: Inferred from expression pattern
17713528 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
17713528 MGI
Cellular Component GO Annotation Evidence References Source
is active in cholinergic synapse IDA
IDA: Inferred from direct assay
15024750 MGI
is active in cholinergic synapse IEP
IEP: Inferred from expression pattern
15024750 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
15024750 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
15024750 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
17713528 MGI
is active in neuromuscular junction IDA
IDA: Inferred from direct assay
15024750 MGI
is active in neuromuscular junction IEP
IEP: Inferred from expression pattern
15024750 MGI
is active in postsynaptic specialization IDA
IDA: Inferred from direct assay
15024750 MGI
is active in postsynaptic specialization IEP
IEP: Inferred from expression pattern
15024750 MGI
located in synapse IDA
IDA: Inferred from direct assay
15024750 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disks large-associated protein 3

  • PSD-95/SAP90-binding protein 3

  • SAP90/PSD 95 associated protein 3

  • discs, large homolog-associated protein 3

  • prion protein ligand 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03803 DLGAP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dlgap3 NCBI NCBI:58512