Dlgap3 - DLG associated protein 3 Gene

Mus musculus

Also known as DAP3; DAP-3; Prpl8; Sapap3

Gene ID: 242667 | Gene type: protein coding

About Dlgap3

Summary

Enables amyloid-beta binding activity. Involved in modification of synaptic structure. Located in glutamatergic synapse and neuromuscular junction. Is active in cholinergic synapse and postsynaptic specialization. Orthologous to human DLGAP3 (DLG associated protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Dlgap3 Products(2)

mRNA	Protein	Name
NM_001302081.1	NP_001289010.1	disks large-associated protein 3
NM_198618.5	NP_941020.1	disks large-associated protein 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables amyloid-beta binding	IDA IDA: Inferred from direct assay	9173930	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in modification of postsynaptic structure	IDA IDA: Inferred from direct assay	17713528	MGI
involved in modification of postsynaptic structure	IEP IEP: Inferred from expression pattern	17713528	MGI
involved in modification of postsynaptic structure	IMP IMP: Inferred from mutant phenotype	17713528	MGI
involved in modulation of chemical synaptic transmission	IDA IDA: Inferred from direct assay	17713528	MGI
involved in modulation of chemical synaptic transmission	IEP IEP: Inferred from expression pattern	17713528	MGI
involved in modulation of chemical synaptic transmission	IMP IMP: Inferred from mutant phenotype	17713528	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in cholinergic synapse	IDA IDA: Inferred from direct assay	15024750	MGI
is active in cholinergic synapse	IEP IEP: Inferred from expression pattern	15024750	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	15024750	MGI
is active in glutamatergic synapse	IEP IEP: Inferred from expression pattern	15024750	MGI
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	17713528	MGI
is active in neuromuscular junction	IDA IDA: Inferred from direct assay	15024750	MGI
is active in neuromuscular junction	IEP IEP: Inferred from expression pattern	15024750	MGI
is active in postsynaptic specialization	IDA IDA: Inferred from direct assay	15024750	MGI
is active in postsynaptic specialization	IEP IEP: Inferred from expression pattern	15024750	MGI
located in synapse	IDA IDA: Inferred from direct assay	15024750	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

disks large-associated protein 3

PSD-95/SAP90-binding protein 3	SAP90/PSD 95 associated protein 3
discs, large homolog-associated protein 3	prion protein ligand 8

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03803	DLGAP3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dlgap3	NCBI	NCBI:58512

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