Padi6 - peptidyl arginine deiminase, type VI Gene

Also Known as P75; Pad6; ePAD; Padi5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 242726

Summary

Enables protein-arginine deiminase activity. Involved in embryonic cleavage. Acts upstream of or within cellular protein metabolic process; cytoplasm organization; and Cytoskeleton organization. Located in cortical granule and intermediate filament Cytoskeleton. Is expressed in 2-cell stage embryo; ileum; and reproductive system. Human ortholog(s) of this gene implicated in infertility. Orthologous to human PADI6 (peptidyl arginine deiminase 6). [provided by Alliance of Genome Resources, Apr 2022]

Padi6 Products (1)

mRNA Protein Name
NM_153106.2 NP_694746.2 protein-arginine deiminase type-6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18463355 MGI
enables protein-arginine deiminase activity IMP
IMP: Inferred from mutant phenotype
17587491 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cytoplasm organization IMP
IMP: Inferred from mutant phenotype
18599511 MGI
acts upstream of or within cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
17587491 MGI
involved in embryonic cleavage IDA
IDA: Inferred from direct assay
16137333 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
18599511 MGI
acts upstream of or within regulation of translation by machinery localization IMP
IMP: Inferred from mutant phenotype
18599511 MGI
Cellular Component GO Annotation Evidence References Source
located in cortical granule IDA
IDA: Inferred from direct assay
16137333 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
12654293 MGI
located in intermediate filament cytoskeleton IDA
IDA: Inferred from direct assay
12654293 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein-arginine deiminase type-6

  • arginine deiminase-like protein

  • egg and embryo abundant PAD

  • peptidyl arginine deiminase, egg and embryo abundant

  • peptidylarginine deiminase VI

  • protein-arginine deiminase type VI

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09964 PADI6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Padi6 NCBI NCBI:353238