2. Gene
  3. Cyp21a1 - cytochrome P450, family 21, subfamily a, polypeptide 1 Gene

Cyp21a1 - cytochrome P450, family 21, subfamily a, polypeptide 1 Gene

  • Gene
  • Protein
  • Agent
Rattus norvegicus

Also known as 21-OH; Cyp21

Gene ID: 24298 | Gene type: protein coding

About Cyp21a1

Summary

Enables steroid 21-monooxygenase activity. Involved in cellular hormone metabolic process; cellular response to peptide hormone stimulus; and response to Antibiotic. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia. Orthologous to several human genes including CYP21A2 (Cytochrome P450 family 21 subfamily A member 2). [provided by Alliance of Genome Resources, Apr 2022]

Cyp21a1 Products(1)

mRNA Protein Name
NM_057101.2 NP_476442.2 steroid 21-hydroxylase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables steroid 21-monooxygenase activity IDA
IDA: Inferred from direct assay
9408081 RGD
Biological Process GO Annotation Evidence Reference Source
involved in C21-steroid hormone biosynthetic process IMP
IMP: Inferred from mutant phenotype
9408081 RGD
involved in cellular response to peptide hormone stimulus IEP
IEP: Inferred from expression pattern
7588239 RGD
involved in mineralocorticoid biosynthetic process IDA
IDA: Inferred from direct assay
19665544 RGD
involved in progesterone metabolic process IDA
IDA: Inferred from direct assay
19665544 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

steroid 21-hydroxylase

21-OHase

Cytochrome P450 subfamily XXI (steroid 21-hydroxylase)

P-450c21

P450-C21

cytochrome P-450c21

cytochrome P450 21 steroid 21 hydroxylase

cytochrome P450 XXI

cytochrome P450, subfamily 21A, polypeptide 1

cytochrome P450, subfamily XXI (stero

Related Agents

Pre-clinical Phase
Bioactive Molecules (17)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120377 CYP1A1 inhibitor 8a Inhibitor 98.00% Unkown
HY-RS03434 CYP11A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03441 CYP1A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03444 CYP20A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03445 CYP21A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03446 CYP24A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03447 CYP26A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03450 CYP27A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03486 CYP51A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16737 Cyp1a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17011 Cyp27a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17479 Cyp11a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19541 Cyp24a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23174 Cyp1a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23454 Cyp27a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23937 Cyp11a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26037 Cyp24a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown