CYP1A1 inhibitor 8a
Based on 1 Customer Validation
CYP1A1 inhibitor 8a is a compound that potently and selectively inhibits the CYP1A1 enzyme and has the potential to prevent cancer. CYP1A1 inhibitor 8a exhibits more than 10-fold selectivity for CYP1A1 and more than 100-fold selectivity over other enzymes in the CYP1 subfamily. CYP1A1 inhibitor 8a can effectively antagonize B[a]P-mediated activation of the aryl hydrocarbon receptor (AhR) in yeast cells and protect human cells from CYP1A1-mediated B[a]P toxicity. CYP1A1 inhibitor 8a has the potential to be developed as a cancer chemopreventive agent.
For research use only. We do not sell to patients.
- Purity: 98.00%
- CAS No.: 1821136-07-5
- Formula: C17H17NO4
- Molecular Weight:299.32
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 1821136-07-5
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Appearance Solid
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Molecular Weight 299.32
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Formula C17H17NO4
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Color Light yellow to yellow
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SMILES
O=C(C1=CC=NC=C1)/C=C/C2=CC(OC)=C(OC)C(OC)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (668.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3409 mL | 16.7045 mL | 33.4091 mL | 83.5226 mL |
| 5 mM | 0.6682 mL | 3.3409 mL | 6.6818 mL | 16.7045 mL | |
| 10 mM | 0.3341 mL | 1.6705 mL | 3.3409 mL | 8.3523 mL | |
| 15 mM | 0.2227 mL | 1.1136 mL | 2.2273 mL | 5.5682 mL | |
| 20 mM | 0.1670 mL | 0.8352 mL | 1.6705 mL | 4.1761 mL | |
| 25 mM | 0.1336 mL | 0.6682 mL | 1.3364 mL | 3.3409 mL | |
| 30 mM | 0.1114 mL | 0.5568 mL | 1.1136 mL | 2.7841 mL | |
| 40 mM | 0.0835 mL | 0.4176 mL | 0.8352 mL | 2.0881 mL | |
| 50 mM | 0.0668 mL | 0.3341 mL | 0.6682 mL | 1.6705 mL | |
| 60 mM | 0.0557 mL | 0.2784 mL | 0.5568 mL | 1.3920 mL | |
| 80 mM | 0.0418 mL | 0.2088 mL | 0.4176 mL | 1.0440 mL | |
| 100 mM | 0.0334 mL | 0.1670 mL | 0.3341 mL | 0.8352 mL |
CYP1A1 inhibitor 8a Related Classifications
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