Nfkbid - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta Gene

Also Known as IkappaBNS; ikB-delta; I-kappa-B-delta

Species: Mus musculus

Gene Type: protein coding
Gene ID: 243910

Summary

Enables NF-kappaB binding activity. Involved in T cell receptor signaling pathway and positive regulation of T-helper 17 cell differentiation. Acts upstream of or within several processes, including negative regulation of NF-kappaB transcription factor activity; negative regulation of T cell differentiation in thymus; and positive regulation of thymocyte apoptotic process. Located in nucleus. Orthologous to human NFKBID (NFKB inhibitor delta). [provided by Alliance of Genome Resources, Apr 2022]

Nfkbid Products (3)

mRNA Protein Name
NM_001360906.1 NP_001347835.1 NF-kappa-B inhibitor delta
NM_001360907.1 NP_001347836.1 NF-kappa-B inhibitor delta
NM_172142.4 NP_742154.1 NF-kappa-B inhibitor delta

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables NF-kappaB binding IPI
IPI: Inferred from physical interaction
11931770 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11931770 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of T cell differentiation in thymus IDA
IDA: Inferred from direct assay
11931770 MGI
involved in T cell receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
25282160 MGI
acts upstream of or within negative regulation of NF-kappaB transcription factor activity IDA
IDA: Inferred from direct assay
11931770 MGI
acts upstream of or within negative regulation of T cell differentiation in thymus IDA
IDA: Inferred from direct assay
11931770 MGI
acts upstream of or within negative regulation of canonical NF-kappaB signal transduction IDA
IDA: Inferred from direct assay
11931770 MGI
involved in positive regulation of T-helper 17 cell differentiation IMP
IMP: Inferred from mutant phenotype
25282160 MGI
acts upstream of or within positive regulation of thymocyte apoptotic process IDA
IDA: Inferred from direct assay
11931770 MGI
acts upstream of thymocyte apoptotic process IDA
IDA: Inferred from direct assay
11931770 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
11931770 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NF-kappa-B inhibitor delta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09262 NFKBID Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfkbid NCBI NCBI:84807