Fat2 - FAT atypical cadherin 2 Gene

Predicted to enable calcium ion binding activity. Predicted to be involved in cell-substrate adhesion; epithelial cell migration; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to act upstream of or within cell adhesion. Predicted to be located in Golgi apparatus; cell junction; and plasma membrane. Predicted to be integral component of membrane. Predicted to be active in adherens junction. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; nose; and urinary system. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 45. Orthologous to human FAT2 (FAT atypical Cadherin 2). [provided by Alliance of Genome Resources, Apr 2022]