2. Gene
  3. Atxn7 - ataxin 7 Gene

Atxn7 - ataxin 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sca7; ataxin-7; A430107N12Rik

Gene ID: 246103 | Gene type: protein coding

About Atxn7

Summary

Enables chromatin binding activity. Acts upstream of or within negative regulation of insulin-like growth factor receptor signaling pathway; negative regulation of phosphorylation; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system; and retina. Used to study spinocerebellar ataxia type 7. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 7. Orthologous to human ATXN7 (ataxin 7). [provided by Alliance of Genome Resources, Apr 2022]

Atxn7 Products(1)

mRNA Protein Name
NM_139227.4 NP_631973.3 ataxin-7
Protein Preferred Names Protein Names

ataxin-7

spinocerebellar ataxia 7 homolog

spinocerebellar ataxia type 7 protein homolog

Atxn7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Atxn7 Q8R4I1 Trrap Mus musculus Q80YV3
Anti Bait CoIP
16494529
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01260 ATXN7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01261 ATXN7L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01262 ATXN7L3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atxn7 NCBI NCBI:6314