Gnal - G protein subunit alpha L Gene

Also Known as Olf; Golf; RGD1305940

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24611

Summary

Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in cellular response to dopamine and regulation of long-term synaptic depression. Predicted to be part of heterotrimeric G-protein complex. Used to study dystonia. Human ortholog(s) of this gene implicated in dystonia 25. Orthologous to human GNAL (G protein subunit alpha L). [provided by Alliance of Genome Resources, Apr 2022]

Gnal Products (1)

mRNA Protein Name
NM_001191836.2 NP_001178765.1 guanine nucleotide-binding protein G(olf) subunit alpha

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to dopamine IMP
IMP: Inferred from mutant phenotype
31678405 RGD
involved in regulation of long-term synaptic depression IMP
IMP: Inferred from mutant phenotype
31678405 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(olf) subunit alpha

  • Olf-alpha protein (olfactory neuron-specific G protein)

  • adenylate cyclase-stimulating G alpha protein, olfactory type

  • guanine nucleotide binding protein, alpha activating activity polypeptide, olfactory type

  • guanine nucleotide binding protein, alpha st

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05537 GNAL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17331 Gnal Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23786 Gnal Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnal NCBI NCBI:2774