2. Gene
  3. Mllt6 - myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6 Gene

Mllt6 - myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Af17

Gene ID: 246198 | Gene type: protein coding

About Mllt6

Summary

Predicted to enable histone binding activity and nucleosome binding activity. Acts upstream of or within several processes, including negative regulation of histone H3-K79 methylation; renal potassium excretion; and renal sodium excretion. Predicted to be active in nucleus. Is expressed in several structures, including early conceptus; forelimb bud; genitourinary system; nervous system; and sensory organ. Orthologous to human MLLT6 (MLLT6, PHD finger containing). [provided by Alliance of Genome Resources, Apr 2022]

Mllt6 Products(1)

mRNA Protein Name
NM_139311.2 NP_647472.2 protein AF-17
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within chromatin organization IMP
IMP: Inferred from mutant phenotype
21546577 MGI
acts upstream of or within negative regulation of urine volume IMP
IMP: Inferred from mutant phenotype
21546577 MGI
acts upstream of or within positive regulation of sodium ion transport IMP
IMP: Inferred from mutant phenotype
21546577 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
21546577 MGI
acts upstream of or within renal potassium excretion IMP
IMP: Inferred from mutant phenotype
21546577 MGI
acts upstream of or within renal sodium excretion IMP
IMP: Inferred from mutant phenotype
21546577 MGI
acts upstream of or within renal system process IMP
IMP: Inferred from mutant phenotype
21546577 MGI
acts upstream of or within renal water absorption IMP
IMP: Inferred from mutant phenotype
21546577 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein AF-17

myeloid/lymphoid or mixed lineage-leukemia translocation to 6 homolog

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

translocated to, 6

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08497 MLLT6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mllt6 NCBI NCBI:4302