Slc25a28 - solute carrier family 25, member 28 Gene

Also Known as Mfrn2; Mrs3/4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 246696

Summary

Enables ferrous iron transmembrane transporter activity. Predicted to be involved in iron import into the mitochondrion. Predicted to act upstream of or within ion transport and iron ion homeostasis. Located in mitochondrion. Is expressed in several structures, including genitourinary system; gut; immune system; liver; and lung. Orthologous to human SLC25A28 (solute carrier family 25 member 28). [provided by Alliance of Genome Resources, Apr 2022]

Slc25a28 Products (2)

mRNA Protein Name
NM_001356944.1 NP_001343873.1 mitoferrin-2 isoform 2
NM_145156.1 NP_660138.1 mitoferrin-2 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ferrous iron transmembrane transporter activity EXP
EXP: Inferred from Experiment
16511496 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
11773964 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitoferrin-2

  • mitochondrial RNA-splicing protein 3/4 homolog

  • mitochondrial iron transporter 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13109 SLC25A28 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20230 Slc25a28 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26737 Slc25a28 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc25a28 NCBI NCBI:81894