1. Gene
  2. Egr4 - early growth response 4 Gene

Egr4 - early growth response 4 Gene

Rattus norvegicus

Also known as Egr4l1; NGFI-C

Gene ID: 25129 | Gene type: protein coding

About Egr4

Summary

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in cellular response to growth factor stimulus and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Biomarker of middle cerebral artery infarction. Orthologous to human EGR4 (early growth response 4). [provided by Alliance of Genome Resources, Apr 2022]

Egr4 Products(1)

mRNA Protein Name
NM_019137.1 NP_062010.1 early growth response protein 4
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
2072895 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to growth factor stimulus IEP
IEP: Inferred from expression pattern
2072895 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
2072895 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

early growth response protein 4

EGR-4

early response protein NGFI-C

nerve growth factor-induced protein C

zinc-finger transcription factor NGFI-C (early response gene)

Orthologs Information

Species Symbol Source ID
Homo sapiens Egr4 NCBI NCBI:1961