Zc3hav1 - zinc finger CCCH-type containing, antiviral 1 Gene

Also Known as Zap; ARTD13; PARP13

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 252832

Summary

Enables RNA binding activity and identical protein binding activity. Involved in several processes, including cellular response to virus; negative regulation of viral genome replication; and regulation of defense response to virus by host. Located in cytoplasm and nucleus. Orthologous to human ZC3HAV1 (zinc finger CCCH-type containing, Antiviral 1). [provided by Alliance of Genome Resources, Apr 2022]

Zc3hav1 Products (2)

mRNA Protein Name
NM_001398725.1 NP_001385654.1 zinc finger CCCH-type antiviral protein 1 isoform 1
NM_173045.3 NP_766633.2 zinc finger CCCH-type antiviral protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
20226086 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
22407013 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
17185417 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to virus IMP
IMP: Inferred from mutant phenotype
20226086 RGD
involved in negative regulation of viral genome replication IDA
IDA: Inferred from direct assay
21876179 RGD
involved in positive regulation of mRNA catabolic process IDA
IDA: Inferred from direct assay
17185417 RGD
involved in regulation of defense response to virus by host IDA
IDA: Inferred from direct assay
12215647 RGD
involved in response to virus IDA
IDA: Inferred from direct assay
21876179 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger CCCH-type antiviral protein 1

  • ADP-ribosyltransferase diphtheria toxin-like 13

  • CCCH-type zinc finger antiviral protein (Zap)

  • inactive Poly [ADP-ribose] polymerase 13

  • rZAP

  • zinc finger CCCH type, antiviral 1

  • zinc finger antiviral protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15997 ZC3HAV1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22055 Zc3hav1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zc3hav1 NCBI NCBI:56829