CNGA2 - Cnga2 cyclic nucleotide gated channel subunit alpha 2 Gene

Rattus norvegicus

Also known as Cncg4; OLFCH

Gene ID: 25411 | Gene type: protein coding

About CNGA2

Summary

Enables cGMP binding activity; identical protein binding activity; and intracellular cyclic nucleotide activated cation channel activity. Involved in membrane depolarization and sensory perception of smell. Located in perikaryon and plasma membrane. Part of intracellular cyclic nucleotide activated cation channel complex. Orthologous to human CNGA2 (cyclic nucleotide gated channel subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

CNGA2 Products(1)

mRNA	Protein	Name
NM_012928.2	NP_037060.2	cyclic nucleotide-gated olfactory channel

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables cGMP binding	IDA IDA: Inferred from direct assay	18048449	RGD
enables identical protein binding	IPI IPI: Inferred from physical interaction	22786723	RGD
enables intracellularly cAMP-activated cation channel activity	IDA IDA: Inferred from direct assay	1697649	RGD
enables intracellularly cGMP-activated cation channel activity	IDA IDA: Inferred from direct assay	1697649	RGD
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	22786723	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in calcium ion transport	IDA IDA: Inferred from direct assay	9878057	RGD
involved in membrane depolarization	IDA IDA: Inferred from direct assay	1697649	RGD
involved in potassium ion transport	IDA IDA: Inferred from direct assay	10377344	RGD
involved in sodium ion transport	IDA IDA: Inferred from direct assay	10377344	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of intracellular cyclic nucleotide activated cation channel complex	IDA IDA: Inferred from direct assay	22786723	RGD
located in non-motile cilium membrane	IDA IDA: Inferred from direct assay	10377344	RGD
located in perikaryon	IDA IDA: Inferred from direct assay	12021210	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cyclic nucleotide-gated olfactory channel

CNG channel alpha-2	CNG-2
CNG2	cyclic nucleotide gated channel 4
cyclic nucleotide gated channel alpha 2	cyclic nucleotide-gated cation channel 2
cyclic nucleotide-gated olfactory channel subunit OCNC1	cyclic nucleotide-gated olfactory channel-like

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-116540	L 858051	Activator	/	Unkown
HY-116540A	L 858051 dihydrochloride	Activator	/	Unkown
HY-RS02880	CNGA2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-175080	8-DY547-cGMP		/	Unkown
HY-RS22448	Cnga2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	CNGA2	NCBI	NCBI:1260

Name
Email *

	Sorry, but the email address you supplied was invalid.