2. Gene
  3. mt-Nd1 - NADH dehydrogenase 1, mitochondrial Gene

mt-Nd1 - NADH dehydrogenase 1, mitochondrial Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus (strain: BN/SsNHsdMCW)

Also known as ND1

Gene ID: 26193 | Gene type: protein coding

About mt-Nd1

Summary

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to contribute to NADH dehydrogenase activity. Involved in response to hydroperoxide; response to organic cyclic compound; and response to xenobiotic stimulus. Located in dendrite; mitochondrion; and neuronal cell body. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including MELAS syndrome; neurodegenerative disease (multiple); optic nerve disease (multiple); toxic shock syndrome; and type 2 diabetes mellitus. Orthologous to human MT-ND1 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

mt-Nd1 Products(2)

mRNA Protein Name
YP_665629.1 NADH dehydrogenase subunit 1 (mitochondrion) [Rattus norvegicus]
YP_665629.1 NADH dehydrogenase subunit 1 (mitochondrion) [Rattus norvegicus]
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in response to hydroperoxide IMP
IMP: Inferred from mutant phenotype
11827750 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
33310031 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
11958534 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
14563825 RGD
Cellular Component GO Annotation Evidence Reference Source
located in dendrite IDA
IDA: Inferred from direct assay
10854284 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
10854284 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADH dehydrogenase subunit 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08796 MT-ND1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens mt-Nd1 NCBI NCBI:4535