Zswim8 - zinc finger SWIM-type containing 8 Gene

Mus musculus

Also known as Kiaa0913; mKIAA0913; 2310021P13Rik; 4832404P21Rik

Gene ID: 268721 | Gene type: protein coding

About Zswim8

Summary

Predicted to enable ubiquitin ligase-substrate adaptor activity. Involved in positive regulation of miRNA catabolic process. Located in cytosol. Part of cullin-RING ubiquitin Ligase complex. Is expressed in central nervous system and retina. Orthologous to human ZSWIM8 (zinc finger SWIM-type containing 8). [provided by Alliance of Genome Resources, Apr 2022]

Zswim8 Products(4)

mRNA	Protein	Name
NM_001252081.2	NP_001239010.1	zinc finger SWIM domain-containing protein 8 isoform 2
NM_001252082.2	NP_001239011.1	zinc finger SWIM domain-containing protein 8 isoform 3
NM_001408318.1	NP_001395247.1	zinc finger SWIM domain-containing protein 8 isoform 4
NM_027996.4	NP_082272.1	zinc finger SWIM domain-containing protein 8 isoform 1

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of miRNA catabolic process	IDA IDA: Inferred from direct assay	33184237	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of cullin-RING ubiquitin ligase complex	IDA IDA: Inferred from direct assay	24012004	MGI
located in cytosol	IDA IDA: Inferred from direct assay	24012004	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

zinc finger SWIM domain-containing protein 8

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16206	ZSWIM8 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Zswim8	NCBI	NCBI:23053

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