Tjp3 - tight junction protein 3 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27375

Summary

Predicted to enable cell adhesion molecule binding activity. Acts upstream of or within regulation of G1/S transition of mitotic cell cycle. Located in several cellular components, including apical plasma membrane; bicellular tight junction; and cytosol. Is expressed in alimentary system epithelium and genitourinary system. Orthologous to human TJP3 (tight junction protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Tjp3 Products (3)

mRNA Protein Name
NM_001282095.1 NP_001269024.1 tight junction protein ZO-3 isoform 2
NM_001282096.1 NP_001269025.1 tight junction protein ZO-3 isoform 1
NM_013769.3 NP_038797.2 tight junction protein ZO-3 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10601346 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of G1/S transition of mitotic cell cycle IGI
IGI: Inferred from genetic interaction
21411630 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
14622136 MGI
located in bicellular tight junction IDA
IDA: Inferred from direct assay
14622136 MGI
located in cell-cell junction IDA
IDA: Inferred from direct assay
25486565 MGI
located in cytosol IDA
IDA: Inferred from direct assay
25486565 MGI
located in nucleus IDA
IDA: Inferred from direct assay
25486565 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tight junction protein ZO-3

  • zona occludens protein 3

  • zonula occludens protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14555 TJP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tjp3 NCBI NCBI:27134