Nelfe - negative elongation factor complex member E, Rdbp Gene

Also Known as RD; Rdbp; NELF-E; D17H6S45

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27632

Summary

Predicted to enable chromatin binding activity. Acts upstream of or within negative regulation of transcription elongation from RNA polymerase II promoter. Predicted to be located in nuclear body and plasma membrane. Predicted to be part of NELF complex. Is expressed in brain and early conceptus. Orthologous to human NELFE (negative elongation factor complex member E). [provided by Alliance of Genome Resources, Apr 2022]

Nelfe Products (3)

mRNA Protein Name
NM_001045863.1 NP_001039328.1 negative elongation factor E
NM_001045864.1 NP_001039329.1 negative elongation factor E
NM_138580.2 NP_613046.2 negative elongation factor E

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
31399344 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22579285 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription elongation by RNA polymerase II IDA
IDA: Inferred from direct assay
31399344 MGI
acts upstream of or within negative regulation of transcription elongation by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
21670248 MGI
Cellular Component GO Annotation Evidence References Source
is active in chromatin IDA
IDA: Inferred from direct assay
31399344 MGI
located in chromatin IDA
IDA: Inferred from direct assay
31399344 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

negative elongation factor E

  • RD RNA-binding protein

  • RNA-binding protein RD

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09203 NELFE Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nelfe NCBI NCBI:7936