AMY2A - amylase alpha 2A Gene

Homo sapiens

Also known as PA; AMY2

Gene ID: 279 | Gene type: protein coding

About AMY2A

Cytogenetic location: 1p21.1 Genomic coordinates (GRCh38): 1:103,616,651-103,625,780 (from NCBI)

This gene has 4 transcripts (splice variants), 194 orthologues and 7 paralogues. Restricted expression toward pancreas (RPKM 19140.7).

Summary

This gene encodes a member of the alpha-amylase family of proteins. Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and Polysaccharides, catalyzing the first step in digestion of dietary starch and glycogen. This gene and several family members are present in a gene cluster on chromosome 1. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jan 2015]

AMY2A Products(1)

mRNA	Protein	Name
NM_000699.4	NP_000690.1	pancreatic alpha-amylase precursor

AMY2A Protein Structure

Alpha-amylase

Alpha-amylase_C

0
100
200
300
400
511 a.a.

Protein Preferred Names

Protein Names

pancreatic alpha-amylase

1,4-alpha-D-glucan glucanohydrolase

Recombinant AMY2A Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76722	AMY2A Protein, Human (HEK293, His)	P04746 (Q16-L511)	≥95%

Related Diseases

Diseases

Alias

Pancreatitis

Mumps Pancreatitis

Ichthyosis, Congenital, Autosomal Recessive 10

Autosomal Recessive Congenital Ichthyosis 10	ARCI10
Ichthyosis, Congenital, Autosomal Recessive, Type 10

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00673	AMY2A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	AMY2A	NCBI

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