2. Gene
  3. Prpf19 - pre-mRNA processing factor 19 Gene

Prpf19 - pre-mRNA processing factor 19 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PSO4; Snev; Prp19; NMP200; D19Wsu55e

Gene ID: 28000 | Gene type: protein coding

About Prpf19

Summary

Predicted to enable identical protein binding activity and ubiquitin-ubiquitin Ligase activity. Involved in proteasomal protein catabolic process. Acts upstream of or within several processes, including inner cell mass cell proliferation; positive regulation of astrocyte differentiation; and positive regulation of mRNA splicing, via spliceosome. Located in cytoplasm; lipid droplet; and nucleus. Is expressed in several structures, including extraembryonic component and genitourinary system. Orthologous to human PRPF19 (pre-mRNA processing factor 19). [provided by Alliance of Genome Resources, Apr 2022]

Prpf19 Products(3)

mRNA Protein Name
NM_001253843.1 NP_001240772.1 pre-mRNA-processing factor 19 isoform 1
NM_001253844.1 NP_001240773.1 pre-mRNA-processing factor 19 isoform 3
NM_134129.4 NP_598890.1 pre-mRNA-processing factor 19 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17349974 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within lipid biosynthetic process IDA
IDA: Inferred from direct assay
17118936 MGI
acts upstream of or within positive regulation of mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
18480465 MGI
involved in proteasomal protein catabolic process IMP
IMP: Inferred from mutant phenotype
17349974 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
18480465 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pre-mRNA-processing factor 19

PRP19/PSO4 homolog

PRP19/PSO4 pre-mRNA processing factor 19 homolog

RING-type E3 ubiquitin transferase PRP19

nuclear matrix protein 200

nuclear matrix protein SNEV

prp19 beta

senescence evasion factor

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11206 PRPF19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prpf19 NCBI NCBI:27339