ACVR2A - activin A receptor type 2A Gene

Bos taurus

Also known as ACVR2

Gene ID: 281598 | Gene type: protein coding

About ACVR2A

Primary_assembly 2: 48,279,649-48,374,634 reverse strand.ARS-UCD1.2:CM008169.2

This gene has 2 transcripts (splice variants), 275 orthologues and 11 paralogues.

mRNA	Protein	Name
NM_174227.3	NP_776652.1	activin receptor type-2A precursor

Activin_recp

STKc_ACVR2a

Protein Preferred Names

Protein Names

activin receptor type-2A

ACTR-IIA	activin A receptor, type II
activin A receptor, type IIA	activin receptor, type IIA

Approval

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99590	Sotatercept		99.94%	Unkown

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-157442	GLPG3312	Antagonist	98.63%	Phase 1
HY-117887	Fidrisertib	Inhibitor	98.17%	Phase 1

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99355	Bimagrumab	Inhibitor	99.31%	Phase 3

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-185430	HM-279	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	ACVR2A	NCBI	NCBI:92
Macaca fascicularis	ACVR2A	NCBI	NCBI:102121129
Mus musculus	ACVR2A	NCBI	NCBI:11480
Rattus norvegicus	ACVR2A	NCBI	NCBI:29263

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