Cux2 - cut-like homeobox 2 Gene

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including positive regulation of nervous system development; regulation of gene expression; and short-term memory. Predicted to act upstream of or within cellular response to organic substance and negative regulation of transcription, DNA-templated. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 67. Orthologous to human CUX2 (cut like homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]