MKX - Mkx mohawk homeobox Gene

Also Known as Irxl1; RGD1305652

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291228

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including cellular response to mechanical stimulus; intratendonous ossification; and negative regulation of cell differentiation. Predicted to be active in nucleus. Orthologous to human MKX (mohawk homeobox). [provided by Alliance of Genome Resources, Apr 2022]

MKX Products (3)

mRNA Protein Name
XM_017600733.2 XP_017456222.2 homeobox protein Mohawk
XM_008771811.3 XP_008770033.2 homeobox protein Mohawk
XM_039096145.1 XP_038952073.1 homeobox protein Mohawk

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to mechanical stimulus IMP
IMP: Inferred from mutant phenotype
27370800 RGD
involved in intratendonous ossification IMP
IMP: Inferred from mutant phenotype
27370800 RGD
involved in negative regulation of chondrocyte differentiation IMP
IMP: Inferred from mutant phenotype
27370800 RGD
involved in negative regulation of fat cell differentiation IMP
IMP: Inferred from mutant phenotype
27370800 RGD
involved in negative regulation of ossification IMP
IMP: Inferred from mutant phenotype
27370800 RGD
involved in tendon cell differentiation IMP
IMP: Inferred from mutant phenotype
27370800 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Mohawk

  • iroquois homeobox protein-like 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08483 MKX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22081 Mkx Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MKX NCBI NCBI:283078