Rit2 - Ras-like without CAAX 2 Gene

Also Known as Rin; Rit1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291713

Summary

Predicted to enable several functions, including Calmodulin binding activity; guanyl ribonucleotide binding activity; and semaphorin receptor binding activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; positive regulation of neuron projection development; and regulation of intracellular signal transduction. Predicted to be located in several cellular components, including cell body; dendritic tree; and membrane raft. Predicted to be active in plasma membrane. Orthologous to human RIT2 (Ras like without CAAX 2). [provided by Alliance of Genome Resources, Apr 2022]

Rit2 Products (1)

mRNA Protein Name
NM_001013060.1 NP_001013078.1 GTP-binding protein Rit2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21957239 RGD
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
18541665 RGD
involved in positive regulation of MAPK cascade IMP
IMP: Inferred from mutant phenotype
16157584 RGD
involved in positive regulation of neuron projection development IGI
IGI: Inferred from genetic interaction
16157584 RGD
involved in positive regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
16157584 RGD
involved in regulation of calcium-mediated signaling IMP
IMP: Inferred from mutant phenotype
14662747 RGD
involved in regulation of protein phosphorylation IGI
IGI: Inferred from genetic interaction
18541665 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GTP-binding protein Rit2

  • Ras-like without CAAX 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12004 RIT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rit2 NCBI NCBI:6014