MACOM - Mecom MDS1 and EVI1 complex locus Gene

Also Known as Evi1; Mds1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 294924

Summary

Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; Histone Methyltransferase activity (H3-K9 specific); and protein homodimerization activity. Predicted to be involved in several processes, including hematopoietic stem cell proliferation; negative regulation of JNK cascade; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including animal organ development; embryonic limb morphogenesis; and positive regulation of brown fat cell differentiation. Predicted to be located in nuclear speck. Predicted to be part of histone deacetylase complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in myeloid neoplasm. Orthologous to human MECOM (MDS1 and EVI1 complex locus). [provided by Alliance of Genome Resources, Apr 2022]

MACOM Products (1)

mRNA Protein Name
NM_001389282.2 NP_001376211.1 histone-lysine N-methyltransferase MECOM
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase MECOM

  • MDS1 and EVI1 complex locus protein EVI1

  • MDS1 and EVI1 complex locus protein MDS1

  • ecotropic viral integration site 1

  • myelodysplasia syndrome 1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07944 MACO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08275 MECOM Human Pre-designed siRNA Set A Pre-designed Set / Unkown