2. Gene
  3. Dync1i1 - dynein cytoplasmic 1 intermediate chain 1 Gene

Dync1i1 - dynein cytoplasmic 1 intermediate chain 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Dnci1; Dncic1; IC74-1A; IC74-1B

Gene ID: 29564 | Gene type: protein coding

About Dync1i1

Summary

Enables microtubule binding activity and microtubule motor activity. Involved in brain development and vesicle transport along microtubule. Located in axon cytoplasm and perinuclear region of cytoplasm. Part of cytoplasmic dynein complex. Colocalizes with piccolo-bassoon transport vesicle. Orthologous to human DYNC1I1 (dynein cytoplasmic 1 intermediate chain 1). [provided by Alliance of Genome Resources, Apr 2022]

Dync1i1 Products(1)

mRNA Protein Name
NM_019234.2 NP_062107.2 cytoplasmic dynein 1 intermediate chain 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables microtubule binding IDA
IDA: Inferred from direct assay
14985359 RGD
enables microtubule motor activity IDA
IDA: Inferred from direct assay
14985359 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14985359 RGD
Biological Process GO Annotation Evidence Reference Source
involved in vesicle transport along microtubule IDA
IDA: Inferred from direct assay
14985359 RGD
Cellular Component GO Annotation Evidence Reference Source
located in axon cytoplasm IDA
IDA: Inferred from direct assay
19380881 RGD
part of cytoplasmic dynein complex IDA
IDA: Inferred from direct assay
1387402 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
14985359 RGD
located in piccolo-bassoon transport vesicle IDA
IDA: Inferred from direct assay
19380881 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytoplasmic dynein 1 intermediate chain 1

DH IC-1

Dnci 1

cytoplasmic dynein intermediate chain 1

dynein cytoplasmic 1 intermediate chain 1A

dynein cytoplasmic 1 intermediate chain 1B

dynein cytoplasmic 1 intermediate chain 1C

dynein cytoplasmic 1 intermediate chain 1D

dynein intermediate c

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04083 DYNC1I1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dync1i1 NCBI NCBI:1780