Serping1 - serpin family G member 1 Gene

Also Known as C1-IA

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 295703

Summary

Predicted to enable complement binding activity and serine-type endopeptidase inhibitor activity. Involved in aging. Located in extracellular space. Used to study glioblastoma. Biomarker of acute myocardial infarction and acute necrotizing pancreatitis. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; angioedema (multiple); cerebral infarction; pancreatitis; and toxic shock syndrome. Orthologous to human SERPING1 (Serpin family G member 1). [provided by Alliance of Genome Resources, Apr 2022]

Serping1 Products (1)

mRNA Protein Name
NM_199093.2 NP_954524.1 plasma protease C1 inhibitor precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
1505923 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

plasma protease C1 inhibitor

  • C1 Inh

  • C1 esterase inhibitor

  • C1-inactivator

  • C1-inhibiting factor

  • C1Inh

  • serine (or cysteine) peptidase inhibitor, clade G, member 1

  • serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)

  • serpin G1

  • serp

Recombinant Serping1 Proteins

Cat. No. Product Name Accession Purity
HY-P73654 Serpin G1 Protein, Rat (HEK293, His) Q6P734/NP_954524.1 (D23-A504) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12694 SERP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12727 SERPING1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18444 Serping1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24926 Serping1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Serping1 NCBI NCBI:710
Mus musculus Serping1 NCBI NCBI:12258