2. Gene
  3. CST4 - Cyss cystatin S Gene

CST4 - Cyss cystatin S Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Cst4

Gene ID: 296234 | Gene type: protein coding

About CST4

Summary

Enables cysteine-type endopeptidase inhibitor activity and protease binding activity. Involved in several processes, including negative regulation of peptidase activity; response to chromate; and response to protozoan. Located in extracellular space and secretory granule. Orthologous to several human genes including CST5 (Cystatin D); CST4 (Cystatin S); and CST2 (cystatin SA). [provided by Alliance of Genome Resources, Apr 2022]

CST4 Products(1)

mRNA Protein Name
NM_198685.2 NP_941958.1 cystatin-S precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables cysteine-type endopeptidase inhibitor activity IDA
IDA: Inferred from direct assay
7575236 RGD
enables protease binding IDA
IDA: Inferred from direct assay
9631169 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cell development IEP
IEP: Inferred from expression pattern
1967932 RGD
involved in cell killing IDA
IDA: Inferred from direct assay
7749605 RGD
involved in negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
8862019 RGD
involved in negative regulation of peptidase activity IDA
IDA: Inferred from direct assay
3263967 RGD
involved in response to axon injury IEP
IEP: Inferred from expression pattern
7878088 RGD
involved in response to chromate IEP
IEP: Inferred from expression pattern
8374010 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
1685882 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
7686006 RGD
involved in response to protozoan IEP
IEP: Inferred from expression pattern
7778093 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
1471486 RGD
involved in salivary gland development IEP
IEP: Inferred from expression pattern
10075146 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
9823730 RGD
located in secretory granule IDA
IDA: Inferred from direct assay
7778093 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cystatin-S

LM protein

cystatin-1

protein LM

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03265 CST4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CST4 NCBI NCBI:1472