2. Gene
  3. Mars1 - methionyl-tRNA synthetase 1 Gene

Mars1 - methionyl-tRNA synthetase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Mars

Gene ID: 299851 | Gene type: protein coding

About Mars1

Summary

Predicted to enable methionine-tRNA Ligase activity. Predicted to be involved in several processes, including RNA metabolic process; cellular response to growth factor stimulus; and positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Part of Aminoacyl-tRNA Synthetase multienzyme complex. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2U. Orthologous to human MARS1 (methionyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mars1 Products(1)

mRNA Protein Name
NM_001127659.1 NP_001121131.1 methionine--tRNA ligase, cytoplasmic
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
27191843 RGD
Cellular Component GO Annotation Evidence Reference Source
part of aminoacyl-tRNA synthetase multienzyme complex IDA
IDA: Inferred from direct assay
19524539 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methionine--tRNA ligase, cytoplasmic

methionine-tRNA synthetase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08153 MARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mars1 NCBI NCBI:4141