Tanc2 - tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 Gene

Also Known as RGD1309285

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 303599

Summary

Involved in dense core granule cytoskeletal transport; regulation of dendritic spine development; and regulation of dendritic spine morphogenesis. Located in dendritic spine. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Orthologous to human TANC2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Tanc2 Products (1)

mRNA Protein Name
NM_001191653.1 NP_001178582.1 protein TANC2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
30021165 RGD
enables structural constituent of postsynaptic density EXP
EXP: Inferred from Experiment
30021165 RGD
enables structural constituent of postsynaptic density IDA
IDA: Inferred from direct assay
30021165 RGD
enables structural constituent of postsynaptic density IMP
IMP: Inferred from mutant phenotype
30021165 RGD
Biological Process GO Annotation Evidence References Source
involved in dense core granule cytoskeletal transport IMP
IMP: Inferred from mutant phenotype
30021165 RGD
involved in regulation of dendritic spine development IMP
IMP: Inferred from mutant phenotype
30021165 RGD
involved in regulation of dendritic spine morphogenesis IMP
IMP: Inferred from mutant phenotype
30021165 RGD
Cellular Component GO Annotation Evidence References Source
located in dendritic spine IDA
IDA: Inferred from direct assay
30021165 RGD
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
30021165 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
21068316 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
21068316 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
30021165 RGD
is active in postsynaptic density IMP
IMP: Inferred from mutant phenotype
30021165 RGD
is active in postsynaptic density, intracellular component IDA
IDA: Inferred from direct assay
21068316 RGD
is active in postsynaptic density, intracellular component IMP
IMP: Inferred from mutant phenotype
21068316 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein TANC2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14195 TANC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tanc2 NCBI NCBI:26115