MAP3K10 - Map3k10 mitogen activated protein kinase kinase kinase 10 Gene

Rattus norvegicus

Also known as Mlk2

Gene ID: 308463 | Gene type: protein coding

About MAP3K10

Summary

Predicted to enable JUN kinase kinase kinase activity; bHLH transcription factor binding activity; and transcription corepressor activity. Involved in cell death and positive regulation of apoptotic process. Predicted to be located in cytoplasm. Orthologous to human MAP3K10 (mitogen-activated protein kinase kinase kinase 10). [provided by Alliance of Genome Resources, Apr 2022]

MAP3K10 Products(1)

mRNA	Protein	Name
NM_001395098.1	NP_001382027.1	mitogen-activated protein kinase kinase kinase 10

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	22128169	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	15069087	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

mitogen-activated protein kinase kinase kinase 10

mitogen-activated protein kinase kinase kinase 10-like

mixed-lineage kinase 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-175809	SRT6	Inhibitor	/	Unkown
HY-RS08047	MAP3K10 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	MAP3K10	NCBI	NCBI:4294

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