MAP3K10 - Map3k10 mitogen activated protein kinase kinase kinase 10 Gene

Also Known as Mlk2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 308463

Summary

Predicted to enable JUN kinase kinase kinase activity; bHLH transcription factor binding activity; and transcription corepressor activity. Involved in cell death and positive regulation of apoptotic process. Predicted to be located in cytoplasm. Orthologous to human MAP3K10 (mitogen-activated protein kinase kinase kinase 10). [provided by Alliance of Genome Resources, Apr 2022]

MAP3K10 Products (1)

mRNA Protein Name
NM_001395098.1 NP_001382027.1 mitogen-activated protein kinase kinase kinase 10

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22128169 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
15069087 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitogen-activated protein kinase kinase kinase 10

  • mitogen-activated protein kinase kinase kinase 10-like

  • mixed-lineage kinase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175809 SRT6 Inhibitor / Unkown
HY-RS08047 MAP3K10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MAP3K10 NCBI NCBI:4294