Ppp2r5b - protein phosphatase 2, regulatory subunit B', beta Gene

Rattus norvegicus

Gene ID: 309179 | Gene type: protein coding

About Ppp2r5b

Summary

Predicted to enable protein Phosphatase activator activity. Acts upstream of or within several processes, including positive regulation of cellular component organization; regulation of protein phosphorylation; and regulation of transcription, DNA-templated. Predicted to be part of protein Phosphatase type 2A complex. Predicted to be active in cytosol and nucleus. Orthologous to human PPP2R5B (protein Phosphatase 2 regulatory subunit B'beta). [provided by Alliance of Genome Resources, Apr 2022]

Ppp2r5b Products(1)

mRNA	Protein	Name
NM_181379.3	NP_852044.1	serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cellular response to growth factor stimulus	IDA IDA: Inferred from direct assay	19029245	RGD
acts upstream of or within negative regulation of G0 to G1 transition	IDA IDA: Inferred from direct assay	19029245	RGD
acts upstream of or within positive regulation of DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	19029245	RGD
acts upstream of or within positive regulation of neuron projection development	IDA IDA: Inferred from direct assay	19029245	RGD
acts upstream of or within positive regulation of neurotrophin TRK receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	19029245	RGD
acts upstream of or within positive regulation of protein-containing complex assembly	IDA IDA: Inferred from direct assay	19029245	RGD
acts upstream of or within positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	19029245	RGD
acts upstream of or within regulation of cell cycle	IDA IDA: Inferred from direct assay	19029245	RGD
acts upstream of or within regulation of peptidyl-tyrosine phosphorylation	IMP IMP: Inferred from mutant phenotype	19029245	RGD
acts upstream of or within regulation of protein autophosphorylation	IDA IDA: Inferred from direct assay	19029245	RGD
acts upstream of or within regulation of protein autophosphorylation	IMP IMP: Inferred from mutant phenotype	19029245	RGD
acts upstream of or within regulation of protein phosphorylation	IDA IDA: Inferred from direct assay	19029245	RGD
acts upstream of or within regulation of protein phosphorylation	IMP IMP: Inferred from mutant phenotype	19029245	RGD
acts upstream of or within regulation of signaling receptor activity	IMP IMP: Inferred from mutant phenotype	19029245	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11019	PPP2R5B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ppp2r5b	NCBI	NCBI:5526

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