Tox2 - TOX high mobility group box family member 2 Gene

Rattus norvegicus

Also known as Gcx1; GCX-1

Gene ID: 311615 | Gene type: protein coding

About Tox2

Summary

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in female gonad development; positive regulation of transcription by RNA polymerase II; and response to gonadotropin. Located in nucleus. Orthologous to human TOX2 (TOX high mobility group box family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Tox2 Products(1)

mRNA	Protein	Name
NM_199392.2	NP_955424.2	TOX high mobility group box family member 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables RNA polymerase II-specific DNA-binding transcription factor binding	IPI IPI: Inferred from physical interaction	14764631	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in female gonad development	IEP IEP: Inferred from expression pattern	14764631	RGD
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	14764631	RGD
involved in response to gonadotropin	IEP IEP: Inferred from expression pattern	14764631	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

TOX high mobility group box family member 2

granulosa cell HMG box protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14909	TOX2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tox2	NCBI	NCBI:84969

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