Sycp2 - synaptonemal complex protein 2 Gene

Also Known as 3830402K23Rik; 4930518F03Rik

Species: Mus musculus

Gene Type: protein coding

Gene ID: 320558

Summary

Predicted to enable DNA binding activity. Acts upstream of or within several processes, including fertilization; male genitalia morphogenesis; and meiotic nuclear division. Located in lateral element. Is expressed in meiotic germ cell of ovary and primary oocyte. Human ortholog(s) of this gene implicated in spermatogenic failure 1. Orthologous to human SYCP2 (synaptonemal complex protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Sycp2 Products (1)

mRNA	Protein	Name
NM_177191.3	NP_796165.2	synaptonemal complex protein 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16717126	MGI

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within animal organ morphogenesis	IMP IMP: Inferred from mutant phenotype	16717126	MGI
acts upstream of apoptotic process	IMP IMP: Inferred from mutant phenotype	16717126	MGI
acts upstream of ectopic germ cell programmed cell death	IMP IMP: Inferred from mutant phenotype	16717126	MGI
acts upstream of or within female meiotic nuclear division	IMP IMP: Inferred from mutant phenotype	16717126	MGI
acts upstream of or within fertilization	IMP IMP: Inferred from mutant phenotype	16717126	MGI
acts upstream of or within male genitalia morphogenesis	IMP IMP: Inferred from mutant phenotype	16717126	MGI
acts upstream of or within male meiotic nuclear division	IMP IMP: Inferred from mutant phenotype	16717126	MGI
acts upstream of or within mitotic G1 phase	IDA IDA: Inferred from direct assay	22164254	MGI
acts upstream of or within negative regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	16717126	MGI
acts upstream of or within negative regulation of developmental process	IMP IMP: Inferred from mutant phenotype	16717126	MGI
acts upstream of or within negative regulation of reproductive process	IMP IMP: Inferred from mutant phenotype	16717126	MGI

Cellular Component GO Annotation	Evidence	References	Source
located in lateral element	IDA IDA: Inferred from direct assay	18283110	MGI
located in synaptonemal complex	IDA IDA: Inferred from direct assay	18316482	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
synaptonemal complex protein 2	SCP-2 synaptonemal complex lateral element protein

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14071	SYCP2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sycp2	NCBI	NCBI:10388