SYCP2 - synaptonemal complex protein 2 Gene

Also Known as SCP2; SCP-2; SPGF1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10388

About SYCP2

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:59,863,571-59,933,637 (from NCBI)

This gene has 9 transcripts (splice variants), 84 orthologues, 1 paralogue and is associated with 1 phenotype. Biased expression in testis (RPKM 17.7), stomach (RPKM 1.7) and 4 other tissues.

Summary

The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex. [provided by RefSeq, Jul 2008]

SYCP2 Products (1)

mRNA Protein Name
NM_014258.4 NP_055073.2 synaptonemal complex protein 2
Protein Preferred Names Protein Names

synaptonemal complex protein 2

  • synaptonemal complex lateral element protein

Related Diseases

Diseases Alias
Spermatogenic Failure 1

  • Oligosynaptic Infertility

  • SPGF1

  • Oligochiasmatic Infertility

  • Oligochiasmic Infertility
Eccrine Papillary Adenocarcinoma

  • Digital Papillary Adenocarcinoma

  • Sweat Gland Adenocarcinoma

  • Digital Papillary Eccrine Carcinoma Of Skin
Eccrine Adenocarcinoma
Tonsil Squamous Cell Carcinoma

  • Tonsillar Squamous Cell Carcinoma

  • Squamous Cell Carcinoma Of Palatine Tonsil
Infertility
Spermatogenic Failure

  • Azoospermia

  • Spgf

  • Spermatogenic Failure, Susceptibility To

  • Absent Sperm

  • Aspermatogenesis

  • Infertility Due To Azoospermia

  • Hypospermatogenesis

  • Azoospermatism
Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome

  • Icf Syndrome

  • Immunodeficiency Syndrome, Variable

  • Ciid

  • Centromeric Instability, Immunodeficiency Syndrome

  • Immune Deficiency, Variable, With Centromeric Instability Of Chromosomes 1, 9, And 16

  • Icf
Premature Menopause

  • Primary Ovarian Insufficiency

  • Premature Ovarian Failure

  • Hypergonadotropic Hypogonadism

  • Premature Ovarian Insufficiency

  • Menopause - Premature

  • Menopause Praecox

  • Menopause Premature

  • Menopause, Premature

  • Female Hypergonadotropic Hypogonadism

  • Hypergonadotrophic Ovarian Failure

  • Primary Female Hypogonadism

  • Pof - [Premature Ovarian Failure]

  • Ovarian Failure

  • Ovarian Secretion Suppression

  • Ovary Hyposecretion

  • Ovary Secretion Deficiency

  • Premature Menopause Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14071 SYCP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SYCP2 MGD MGI:1933281
Rattus norvegicus SYCP2 RGD RGD:69429
Macaca mulatta SYCP2 VGNC VGNC:98454
Felis catus SYCP2 VGNC VGNC:65874
Canis familiaris SYCP2 VGNC VGNC:47019
Bos taurus SYCP2 VGNC VGNC:35509