ZAR1 - zygote arrest 1 Gene

Also Known as Z3CXXC6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 326340

About ZAR1

Cytogenetic location: 4p11 Genomic coordinates (GRCh38): 4:48,490,252-48,497,635 (from NCBI)

This gene has 1 transcript (splice variant), 177 orthologues and 1 paralogue. Low expression observed in reference dataset.

Summary

This maternal effect gene is oocyte-specific and encodes a protein that is thought to function in the initiation of embryogenesis. A similar protein in mouse is required for female fertility. [provided by RefSeq, Jul 2013]

ZAR1 Products (1)

mRNA Protein Name
NM_175619.3 NP_783318.1 zygote arrest protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZAR1 Protein Structure

zf-3CxxC

zf-3CxxC: Zinc-binding domain (325 - 409)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 424 a.a.
Protein Preferred Names Protein Names

zygote arrest protein 1

  • oocyte-specific maternal effect factor

ZAR1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZAR1 Q86SH2 DYNLL2 Homo sapiens Q96FJ2
Validated Y2H
32296183
Intra
ZAR1 Q86SH2 DYNLL2 Homo sapiens Q96FJ2
Y2H Array
32296183
Intra
ZAR1 Q86SH2 DYNLL2 Homo sapiens Q96FJ2
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Meningothelial Meningioma

  • Meningotheliomatous Meningioma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15952 ZAR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ZAR1 RGD RGD:727972
Mus musculus ZAR1 MGD MGI:2180337
Canis familiaris ZAR1 VGNC VGNC:53507
Felis catus ZAR1 VGNC VGNC:80119
Bos taurus ZAR1 VGNC VGNC:37051
Macaca mulatta ZAR1 VGNC VGNC:79251
Others ZAR1 NCBI