Hsf5 - heat shock transcription factor family member 5 Gene

Mus musculus

Also known as Gm739; MLZ-220

Gene ID: 327992 | Gene type: protein coding

About Hsf5

Summary

Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human HSF5 (heat shock transcription factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Hsf5 Products(1)

mRNA	Protein	Name
NM_001045527.1	NP_001038992.1	heat shock factor protein 5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription activator activity	IMP IMP: Inferred from mutant phenotype	38684656	MGI
enables DNA-binding transcription repressor activity	IMP IMP: Inferred from mutant phenotype	38684656	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in male meiotic nuclear division	IMP IMP: Inferred from mutant phenotype	37206036	MGI
involved in spermatogenesis	IMP IMP: Inferred from mutant phenotype	37206036	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in XY body	IDA IDA: Inferred from direct assay	37206036	MGI
located in nucleus	IDA IDA: Inferred from direct assay	38684656	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

heat shock factor protein 5

HSF 5	HSTF 5
heat shock transcription factor 5	protein expressed in male leptotene and zygotene spermatocytes 220

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06412	HSF5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hsf5	NCBI	NCBI:124535

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