HSF5 - heat shock transcription factor 5 Gene
Also Known as HSF 5; HSTF 5
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 124535
About HSF5
This gene has 1 transcript (splice variant), 199 orthologues and 9 paralogues. Restricted expression toward testis (RPKM 33.9).
Summary
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
HSF5 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001080439.3 | NP_001073908.2 | heat shock factor protein 5 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables sequence-specific double-stranded DNA binding |
IDA
IDA: Inferred from direct assay
|
28473536 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
HSF5 Protein Structure
HSF_DNA-bind
HSF_DNA-bind: HSF-type DNA-binding (69 - 132)
- 0
- 100
- 200
- 300
- 400
- 500
- 596 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
heat shock factor protein 5 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Spermatogenic Failure 23 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS06412 | HSF5 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | HSF5 | VGNC | VGNC:41817 |
| Rattus norvegicus | HSF5 | RGD | RGD:1592448 |
| Macaca mulatta | HSF5 | VGNC | VGNC:73446 |
| Mus musculus | HSF5 | MGD | MGI:2685585 |
| Bos taurus | HSF5 | VGNC | VGNC:29985 |
| Others | HSF5 | NCBI |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service