2. Gene
  3. Zmiz1 - zinc finger, MIZ-type containing 1 Gene

Zmiz1 - zinc finger, MIZ-type containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Rai17; Zimp10; Gm10397; E330020C23; I920194n01

Gene ID: 328365 | Gene type: protein coding

About Zmiz1

Summary

Predicted to enable SMAD binding activity and nuclear receptor coactivator activity. Involved in positive regulation of Notch signaling pathway and positive regulation of T cell differentiation. Acts upstream of or within several processes, including circulatory system development; positive regulation of fibroblast proliferation; and vitellogenesis. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including embryo ectoderm; genitourinary system; limb; limb bud; and sensory organ. Orthologous to human ZMIZ1 (zinc finger MIZ-type containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Zmiz1 Products(2)

mRNA Protein Name
NM_001310666.1 NP_001297595.1 zinc finger MIZ domain-containing protein 1 isoform 2
NM_183208.4 NP_899031.2 zinc finger MIZ domain-containing protein 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
26163108 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within artery morphogenesis IMP
IMP: Inferred from mutant phenotype
17967885 MGI
acts upstream of or within cellular senescence IDA
IDA: Inferred from direct assay
15572682 MGI
acts upstream of or within developmental growth IMP
IMP: Inferred from mutant phenotype
17967885 MGI
acts upstream of or within heart morphogenesis IMP
IMP: Inferred from mutant phenotype
17967885 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
17967885 MGI
involved in positive regulation of Notch signaling pathway IMP
IMP: Inferred from mutant phenotype
26522984 MGI
involved in positive regulation of T cell differentiation IMP
IMP: Inferred from mutant phenotype
26522984 MGI
acts upstream of or within positive regulation of fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
17967885 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
17967885 MGI
acts upstream of or within vasculogenesis IMP
IMP: Inferred from mutant phenotype
17967885 MGI
acts upstream of or within vitellogenesis IMP
IMP: Inferred from mutant phenotype
17967885 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger MIZ domain-containing protein 1

PIAS-like protein Zimp10

retinoic acid induced 17

retinoic acid-induced protein 17

Zmiz1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Zmiz1 Q6P1E1 Smarca4 Mus musculus Q3TKT4
Anti Bait CoIP
26163108
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16087 ZMIZ1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zmiz1 NCBI NCBI:57178