Lhfpl5 - lipoma HMGIC fusion partner-like 5 Gene

Also Known as Tmhs; hscy; 9330179O15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 328789

Summary

Acts upstream of or within auditory receptor cell stereocilium organization and detection of mechanical stimulus involved in sensory perception of sound. Located in apical plasma membrane and stereocilium tip. Is expressed in several structures, including cranial ganglion; genitourinary system; inner ear; lung; and superior cervical ganglion. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 67. Orthologous to human LHFPL5 (LHFPL tetraspan subfamily member 5). [provided by Alliance of Genome Resources, Apr 2022]

Lhfpl5 Products (1)

mRNA Protein Name
NM_026571.2 NP_080847.2 LHFPL tetraspan subfamily member 5 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23217710 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within auditory receptor cell stereocilium organization IMP
IMP: Inferred from mutant phenotype
15905332 MGI
acts upstream of or within detection of mechanical stimulus involved in sensory perception of sound IMP
IMP: Inferred from mutant phenotype
23217710 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
15905332 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
15905332 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
23217710 MGI
located in stereocilium bundle IDA
IDA: Inferred from direct assay
17876667 MGI
located in stereocilium tip IDA
IDA: Inferred from direct assay
23217710 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

LHFPL tetraspan subfamily member 5 protein

  • lipoma HMGIC fusion partner-like 5 protein

  • tetraspan membrane protein of hair cell stereocilia

  • tetraspan transmembrane protein, hair cell stereocilia

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07629 LHFPL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lhfpl5 NCBI NCBI:222662