Dennd1b - DENN domain containing 1B Gene

Also Known as 4632404N19Rik; 4930467M19Rik; 6820401H01Rik; F730008N07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 329260

Summary

Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in endocytic recycling; positive regulation of GTPase activity; and positive regulation of immune response. Predicted to be located in cytoplasmic vesicle. Predicted to be active in cytosol and nuclear speck. Orthologous to human DENND1B (DENN domain containing 1B). [provided by Alliance of Genome Resources, Apr 2022]

Dennd1b Products (2)

mRNA Protein Name
NM_001166501.1 NP_001159973.1 DENN domain-containing protein 1B isoform 1
NM_181347.3 NP_851992.1 DENN domain-containing protein 1B isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables guanyl-nucleotide exchange factor activity IMP
IMP: Inferred from mutant phenotype
26774822 MGI
enables small GTPase binding IPI
IPI: Inferred from physical interaction
26774822 MGI
Biological Process GO Annotation Evidence References Source
involved in T cell receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
26774822 MGI
involved in endocytic recycling IMP
IMP: Inferred from mutant phenotype
26774822 MGI
involved in positive regulation of GTPase activity IMP
IMP: Inferred from mutant phenotype
26774822 MGI
involved in positive regulation of T-helper 2 cell cytokine production IMP
IMP: Inferred from mutant phenotype
26774822 MGI
involved in regulation of immune response IMP
IMP: Inferred from mutant phenotype
26774822 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DENN domain-containing protein 1B

  • ASL1/9AS1-1 fusion

  • DENN/MADD domain containing 1B

  • connecdenn 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03686 DENND1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dennd1b NCBI NCBI:163486