Tafa3 - TAFA chemokine like family member 3 Gene

Also Known as Sam3; Tafa-3; Fam19a3; 7530404M11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 329731

Summary

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]

Tafa3 Products (1)

mRNA Protein Name
NM_183224.3 NP_899047.1 chemokine-like protein TAFA-3 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of microglial cell activation IDA
IDA: Inferred from direct assay
25595455 MGI
acts upstream of or within positive regulation of microglial cell activation IDA
IDA: Inferred from direct assay
25595455 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
22426341 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chemokine-like protein TAFA-3

  • family with sequence similarity 19, member A3

  • protein FAM19A3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14181 TAFA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tafa3 NCBI NCBI:284467