2. Gene
  3. Tafa3 - TAFA chemokine like family member 3 Gene

Tafa3 - TAFA chemokine like family member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sam3; Tafa-3; Fam19a3; 7530404M11Rik

Gene ID: 329731 | Gene type: protein coding

About Tafa3

Summary

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]

Tafa3 Products(1)

mRNA Protein Name
NM_183224.3 NP_899047.1 chemokine-like protein TAFA-3 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within negative regulation of microglial cell activation IDA
IDA: Inferred from direct assay
25595455 MGI
acts upstream of or within positive regulation of microglial cell activation IDA
IDA: Inferred from direct assay
25595455 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
22426341 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chemokine-like protein TAFA-3

family with sequence similarity 19, member A3

protein FAM19A3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14181 TAFA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tafa3 NCBI NCBI:284467