Acot11 - acyl-CoA thioesterase 11 Gene

Also Known as BFIT; Thea; BFIT1; Them1; mKIAA0707; 1110020M10Rik; 2010309H15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 329910

Summary

Predicted to enable long-chain acyl-CoA hydrolase activity; long-chain fatty acyl-CoA binding activity; and palmitoyl-CoA hydrolase activity. Involved in negative regulation of cold-induced thermogenesis. Acts upstream of or within response to cold. Predicted to be located in mitochondrial matrix. Predicted to be active in cytosol. Orthologous to human ACOT11 (acyl-CoA thioesterase 11). [provided by Alliance of Genome Resources, Apr 2022]

Acot11 Products (2)

mRNA Protein Name
NM_001347159.1 NP_001334088.1 acyl-coenzyme A thioesterase 11 isoform 1
NM_025590.4 NP_079866.2 acyl-coenzyme A thioesterase 11 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
27110486 MGI
involved in response to cold IEP
IEP: Inferred from expression pattern
11696000 MGI
involved in response to temperature stimulus IEP
IEP: Inferred from expression pattern
11696000 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acyl-coenzyme A thioesterase 11

  • acyl-CoA thioester hydrolase 11

  • adipose-associated thioesterase

  • brown fat-inducible thioesterase

  • palmitoyl-coenzyme A thioesterase

  • thioesterase, adipose associated

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00174 ACOT11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acot11 NCBI NCBI:26027