Gmppb - GDP-mannose pyrophosphorylase B Gene

Also Known as E430010H19

Species: Mus musculus

Gene Type: protein coding
Gene ID: 331026

Summary

Predicted to enable mannose-1-phosphate guanylyltransferase activity. Predicted to be involved in GDP-mannose biosynthetic process; cell wall mannoprotein biosynthetic process; and protein glycosylation. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2T; congenital muscular dystrophy-dystroglycanopathy A14; and muscular dystrophy-dystroglycanopathy. Orthologous to human GMPPB (GDP-mannose pyrophosphorylase B). [provided by Alliance of Genome Resources, Apr 2022]

Gmppb Products (3)

mRNA Protein Name
NM_001357682.2 NP_001344611.1 mannose-1-phosphate guanyltransferase beta
NM_001410629.1 NP_001397558.1 mannose-1-phosphate guanyltransferase beta
NM_177910.5 NP_808578.1 mannose-1-phosphate guanyltransferase beta

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in GDP-mannose biosynthetic process IMP
IMP: Inferred from mutant phenotype
38419795 MGI
involved in GDP-mannose biosynthetic process from glucose IMP
IMP: Inferred from mutant phenotype
38419795 MGI
involved in GDP-mannose biosynthetic process from mannose IMP
IMP: Inferred from mutant phenotype
38419795 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
38419795 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mannose-1-phosphate guanyltransferase beta

  • GTP-mannose-1-phosphate guanylyltransferase beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05525 GMPPB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gmppb NCBI NCBI:29925