A4gnt - alpha-1,4-N-acetylglucosaminyltransferase Gene

Also Known as Gm798; Alpha4gnt

Species: Mus musculus

Gene Type: protein coding
Gene ID: 333424

Summary

This gene encodes a protein from the Glycosyltransferase 32 family. The encoded enzyme catalyzes the transfer of N-acetylglucosamine to alpha-1,4-linked beta-galactose residues. This enzyme is required for type III Mucin synthesis and it is largely associated with the Golgi apparatus membrane. The encoded protein appears to be expressed in adenocarcinoma cells of pancreatic, biliary tract and gastric cancers.[provided by RefSeq, Jan 2010]

A4gnt Products (1)

mRNA Protein Name
NM_001077424.2 NP_001070892.1 alpha-1,4-N-acetylglucosaminyltransferase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables acetylglucosaminyltransferase activity IMP
IMP: Inferred from mutant phenotype
22307328 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
22307328 MGI
acts upstream of or within negative regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
22307328 MGI
acts upstream of or within protein O-linked glycosylation IMP
IMP: Inferred from mutant phenotype
22307328 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-1,4-N-acetylglucosaminyltransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70140 α-1,4-N-Acetylglucosaminyltransferase 4 Inhibitor / Unkown
HY-RS00014 A4GNT Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens A4gnt NCBI NCBI:51146