A4gnt - alpha-1,4-N-acetylglucosaminyltransferase Gene

Mus musculus

Also known as Gm798; Alpha4gnt

Gene ID: 333424 | Gene type: protein coding

About A4gnt

Summary

This gene encodes a protein from the Glycosyltransferase 32 family. The encoded enzyme catalyzes the transfer of N-acetylglucosamine to alpha-1,4-linked beta-galactose residues. This enzyme is required for type III Mucin synthesis and it is largely associated with the Golgi apparatus membrane. The encoded protein appears to be expressed in adenocarcinoma cells of pancreatic, biliary tract and gastric cancers.[provided by RefSeq, Jan 2010]

A4gnt Products(1)

mRNA	Protein	Name
NM_001077424.2	NP_001070892.1	alpha-1,4-N-acetylglucosaminyltransferase

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables acetylglucosaminyltransferase activity	IMP IMP: Inferred from mutant phenotype	22307328	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of epithelial cell proliferation	IMP IMP: Inferred from mutant phenotype	22307328	MGI
acts upstream of or within negative regulation of epithelial cell proliferation	IMP IMP: Inferred from mutant phenotype	22307328	MGI
acts upstream of or within protein O-linked glycosylation	IMP IMP: Inferred from mutant phenotype	22307328	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

alpha-1,4-N-acetylglucosaminyltransferase

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-E70140	α-1,4-N-Acetylglucosaminyltransferase 4	Inhibitor	/	Unkown
HY-RS00014	A4GNT Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	A4gnt	NCBI	NCBI:51146

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